Cardiomyocyte Cell Cycle Dynamics 

Developmental cardiac tissue contains cardiomyocytes that can proliferate and repair the heart after injury. In contrast, adult heart largely loses its ability to repair with cardiomyocytes unable to reenter the cell cycle. Whether cardiomyocytes can be reverted into developmental proliferative state with consequences for cardiac repair remains untested. The lab utilizes in vitro cellular models and mouse transgenesis to characterize cardiomyocyte reprogramming together with accurate measurement of molecular and functional responses 

  • Facebook Clean Grey
  • LinkedIn Social Icon
PubMed logo.png

Temple University

Lewis Katz School of Medicine