Cardiac derived stem-like cells for heart repair
Cardiac Progenitor cells (CPCs) are resident stem cells of the heart. Preclinical and Clinical studies provide evidence towards a beneficial role of CPCs for improvement of cardiac structure and function. The goal of this project;
Understand the basic molecular and cellular function of CPCs isolated and expanded in culture from mouse and human hearts
Determine the effect of age and disease on CPC morphological and functional characteristics.
Finally, we are currently developing strategies to enhances CPC based therapies to overcome limitations and challenges to